Polycystic Ovaries Research Today is a free monthly online journal that collates and summarizes the latest research about Polycystic Ovaries, including details on treatment, symptoms, polycystic ovary syndrome, infertility.

Beneficial effect of metformin on pregnancy outcome in women with polycystic ovary syndrome is not associated with major changes in C-reactive protein levels or indices of coagulation.

Vanky E, Salvesen KA, Hjorth-Hansen H, Bjerve K, Carlsen SM

Department of Obstetrics and Gynaecology, Norwegian University of Science and Technology, Trondheim, Norway. eszter.vanky@medisin.ntnu.no

In women with polycystic ovary syndrome, C-reactive protein levels and D-dimer, antithrombin III, activated protein C resistance, and activated partial thromboplastin time were unaffected by metformin treatment throughout pregnancy. Protein C levels increased slightly in the metformin group compared with the placebo group.

Published 27 February 2006 in Fertil Steril, 85(3): 770-4.
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