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Candidate genes in women with polycystic ovary syndrome.

Franks S

Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Hospital, London, United Kingdom. s.franks@imperial.ac.uk

There is plentiful evidence that genetic factors have an important part to play in the etiology of polycystic ovary syndrome. As yet, however, none of the potential candidate loci have withstood the scrutiny of large case-control studies, although studies of a locus close to the insulin receptor gene on chromosome 19p are emerging as promising.

Published 26 June 2006 in Fertil Steril, 86: S15.
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