Polycystic Ovaries Research Today is a free monthly online journal that collates and summarizes the latest research about Polycystic Ovaries, including details on treatment, symptoms, polycystic ovary syndrome, infertility.

Prospective, randomized trial of metformin and vitamins for the reduction of plasma homocysteine in insulin-resistant polycystic ovary syndrome.

Schachter M, Raziel A, Strassburger D, Rotem C, Ron-El R, Friedler S

In Vitro Fertilization and Infertility Unit, Assaf Harofeh Medical Center, Tel Aviv University, Zerifin, Israel. ivfdoc@asaf.health.gov.il

One hundred and two women with insulin-resistant polycystic ovary syndrome were randomized to treatment with a vitamin B preparation, metformin, or both, in conjunction with standard infertility treatment. Plasma homocysteine levels were significantly reduced by both B vitamins and metformin, but to a greater degree by B vitamins, and higher pregnancy rates were associated with vitamin B treatment.

Published 6 July 2007 in Fertil Steril, 88(1): 227-30.
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